Formulation and characterization of lornoxicam-loaded cellulosic-microsponge gel for possible applications in arthritis
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Lornoxicam Microsponge Tablets for the Treatment of Arthritis
The purpose of this study was to design novel drug delivery system containing Lornoxicam microsponges. Lornoxicam is a Non-steroidal anti-inflammatory drug used for the treatment of various inflammatory diseases. Microsponges containing Lornoxicam and Eudragit RS 100 were prepared by quasi emulsion solvent diffusion method. The effects of drug to polymer ratios on physical characteristics of th...
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The objective of present work was to formulate and evaluate Fluconazole (FLZ) microsponges using quasi emulsion solvent diffusion technique and microsponge gel by using carbopol. Microsponges containing FLZ were obtained successfully with different proportions of ethyl cellulose polymer (EC). The formulations were studied for particle size and physical characterization. The physical characteriz...
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Non-Steroidal Anti-inflammatory drugs (NSAIDs), including selective cyclooxygenase (COX)-2 inhibitors, have come to play an important role in the pharmacologic management of musculoskeletal disorders. Clinical trials have established the efficacy of etoricoxib in Osteoarthritis, Rheumatoid Arthritis, Acute Gouty Arthritis, Ankylosing Spondylitis, Low back pain, acute postoperative pain, and pri...
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Invasive fungal infections can be devastating, especially in immunocompromized patients. Oral administration of fluconazole (FLZ) often produces gastric irritation, heart-burn, vomiting and sometimes patient can develop ulceration resulting in a less patient compliance with long term therapy. The aim of the present study was to formulate topical microsponge-based delivery system containing FLZ ...
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Background: Nowadays transdermal drug delivery systems (TDDS), as an appropriate replacement for oral and parenteral dosage forms, are developing. These systems which designed to transport drugs through skin layers into the systemic circulation, have several benefits such as avoiding first-pass metabolism, sustained and controlled drug release, reducing side effects, and ease of use. The aim of...
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ژورنال
عنوان ژورنال: Saudi Pharmaceutical Journal
سال: 2020
ISSN: 1319-0164
DOI: 10.1016/j.jsps.2020.06.021